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Matrixyl (palmitoyl peptides)

Last checked 21 Oct 2026

A family of peptide ingredients made for skincare. You'll find them in serums and moisturisers, usually listed by their chemical name.

  • Also calledPalmitoyl pentapeptide-4, Matrixyl 3000, Matrixyl Synthe'6
  • Commonly discussed forSkin that looks smoother and firmer (cosmetic use)
  • Lab reportsNot listed

A cosmetic skincare ingredient.

In plain English

Matrixyl is a trade name for a group of lab-made peptides, such as palmitoyl pentapeptide-4 and palmitoyl tripeptide-1. Skincare brands add them to serums and creams for a smoother, firmer look. They're cosmetic ingredients, not medicines, so the label claims are about how skin looks and feels. Some brands state a percentage and some don't. If a product doesn't say how much it contains, compare it with others that do.