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Argireline
Last checked 21 Oct 2026A peptide ingredient used in skincare serums. You'll see it on labels as acetyl hexapeptide-8.
- Also calledAcetyl hexapeptide-8, acetyl hexapeptide-3
- Commonly discussed forThe look of expression lines (cosmetic use)
- Lab reportsNot listed
A cosmetic skincare ingredient.
In plain English
Argireline is a lab-made peptide that skincare brands use in serums aimed at the look of expression lines, such as frown lines and crow's feet. It's a cosmetic ingredient, so products make claims about appearance only. Results in published studies are modest and mostly come from small trials run or funded by ingredient makers. A serum that states its percentage makes it easier to compare one product with another.